O058 Characteristics and prognosis of cerebrovascular fibromuscular dysplasia (FMD) - a retrospective cohort study

Abstract Introduction Fibromuscular dysplasia (FMD) is a rare, non-atherosclerotic, non-inflammatory vascular disorder that primarily affects renal and cerebrovascular vessels. Limited data are available on the clinical characteristics of FMD, particularly from UK/Europe. Methods We performed retrospective cohort analysis all cases carotid/cerebrovascular FMD presenting to our regional service, by case-note review, searching relevant databases. Results Eighty-six patients were identified between 1998–2020. Stroke or TIA was most common mode presentation. The frequent pattern bilateral extracranial internal carotid artery FMD. Concomitant complications - dissection, aneurysm occlusive disease carotid, vertebral cerebral vessels (41%) included two cavernous fistula. also observed in renal/visceral aorta 13(15%) (60% those who had imaging), with 5% having dissection other 19(22%) required intervention (mainly for intracranial aneurysm), 10% requiring complications. Recurrent events (stroke/TIAs aneurysmal intervention) seen 23% cases. Overall mortality 7% over median follow-up period 47 months. Conclusion co-existence high requires careful surveillance. Vascular beds probably under-estimated. would recommend low threshold routine imaging Take-home message rare but when as stroke, may be involved,